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primary immunodeficiency

and other rare immune diseases

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Stanford Alliance for Primary Immunodeficiencies and Rare Immune Diseases (SAPI)

Primary Immunodeficiencies (PI) are rare diseases of the immune system that affects children and adults and increases the susceptibility to infection, allergy, auto-inflammation, autoimmunity, and cancers. There are over 200 of these immune diseases recognized, and many more are being discovered every day, including here at Stanford.

SAPI is an advocacy group founded by parents and doctors at Stanford with three main goals: Advocacy, Education, and Research. We run events such as Bowling days and the Summer Scamper to reduce the isolation patients with PI feel. We hold Q&A days to educate patients and doctors about these rare diseases. We raise funds to direct research into improving diagnosis, treatment, and cure of these diseases at Stanford. <em?Join us!

Is it just an infection?

Primary immune deficiencies should be suspected whenever anyone has:

  • serious infections (ones that requires hospitalization, or IV antibiotics or antivirals)
  • recurrent infections (infections that reoccur frequently), or
  • opportunistic or unusual infections (unusual organisms that do not ordinarily infect healthy people)
  • severe allergies
  • unusual or severe autoimmune diseases (e.g., cytopenias, granulomatous diseases)

At Stanford University, we are interested in diagnosing and treating primary immune deficiency diseases. Our faculty and staff dedicate their professional lives to these disorders and are known across the world for their research and clinical expertise. Because PIDs are difficult to diagnose, the knowledge and experience of a trained team are often necessary.

If you suspect you or your child has a PI, we are here to help. With prompt diagnosis and treatment, you or your child can live a healthy and productive life. Our Immunology Clinic utilizes the latest diagnostic methods and treatment modalities to ensure you or your child receives prompt attention and care. We work with specialists in gastroenterology, pulmonary medicine, infectious diseases, oncology, as well as practitioners in alternative medicine, to ensure integrated and thoughtful treatments for these chronic conditions.