primary immunodeficiency


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Primary Immunodeficiencies (PI) are diseases of children and adults that increase the susceptibility to infection, autoimmune diseases, and cancers. There are over 180 PI diseases recognized, and many more are being discovered every day.

Is it just an infection?

Primary immune deficiencies should be suspected whenever anyone has:

  • serious infections (ones that requires hospitalization, or IV antibiotics or antivirals)
  • recurrent infections (infections that reoccur frequently), or
  • opportunistic or unusual infections (unusual organisms that do not ordinarily infect healthy people)
  • severe allergies
  • unusual or severe autoimmune diseases (e.g., cytopenias, granulomatous diseases)

At Stanford University, we are interested in diagnosing and treating primary immune deficiency diseases. Our faculty and staff dedicate their professional lives to these disorders and are known across the world for their research and clinical expertise. Because PIDs are difficult to diagnose, the knowledge and experience of a trained team are often necessary.

If you suspect you or your child has a PI, we are here to help. With prompt diagnosis and treatment, you or your child can live a healthy and productive life. Our Immunology Clinic utilizes the latest diagnostic methods and treatment modalities to ensure you or your child receives prompt attention and care. We work with specialists in gastroenterology, pulmonary medicine, infectious diseases, oncology, as well as practitioners in alternative medicine, to ensure integrated and thoughtful treatments for these chronic conditions.